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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
1.52
Human Site:
Y146
Identified Species:
2.78
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
Y146
L
Q
Q
T
L
A
T
Y
L
Q
C
M
R
H
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
W63
P
I
V
S
E
E
E
W
A
H
T
K
Q
L
V
Dog
Lupus familis
XP_543902
686
76910
E123
T
L
Q
Q
K
L
L
E
R
Q
E
K
T
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
E78
T
L
Q
E
K
L
L
E
R
Q
E
K
T
A
N
Rat
Rattus norvegicus
P32738
640
71845
E77
T
L
Q
E
K
L
L
E
R
Q
E
K
T
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
D80
S
L
Q
Q
K
L
L
D
R
R
E
K
T
A
N
Chicken
Gallus gallus
Q90YJ9
640
72605
E77
S
L
Q
L
I
L
E
E
R
R
E
E
T
T
N
Frog
Xenopus laevis
Q7ZXE1
659
74538
Q96
F
Q
N
G
V
G
K
Q
L
H
E
E
L
V
Q
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
S74
Q
K
K
L
L
E
R
S
E
Q
K
A
N
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
G131
R
Q
F
S
A
P
Q
G
I
G
A
R
L
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
A64
A
H
K
F
V
R
Q
A
T
P
L
Q
E
Q
L
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
R112
Q
Q
K
I
V
E
M
R
E
T
K
V
N
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
Q107
V
E
T
F
E
R
Q
Q
L
L
C
K
D
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
0
13.3
N.A.
13.3
13.3
N.A.
6.6
6.6
13.3
13.3
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
26.6
13.3
N.A.
13.3
13.3
N.A.
13.3
20
20
33.3
N.A.
26.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
8
8
0
8
8
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
16
16
24
16
31
16
0
47
16
8
0
0
% E
% Phe:
8
0
8
16
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
16
0
0
0
16
0
% H
% Ile:
0
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
24
0
31
0
8
0
0
0
16
47
0
0
0
% K
% Leu:
8
39
0
16
16
39
31
0
24
8
8
0
16
8
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
39
% N
% Pro:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
16
31
47
16
0
0
24
16
0
39
0
8
8
8
16
% Q
% Arg:
8
0
0
0
0
16
8
8
39
16
0
8
8
0
0
% R
% Ser:
16
0
0
16
0
0
0
8
0
0
0
0
0
0
8
% S
% Thr:
24
0
8
8
0
0
8
0
8
8
8
0
39
8
8
% T
% Val:
8
0
8
0
24
0
0
0
0
0
0
8
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _